fbpx
A peer-reviewed journal that offers evidence-based clinical information and continuing education for dentists.

Researchers Identify Protein Behind Mechanism Responsible for Bone Loss

In a development that may have implications for treating periodontal disease, a team from the University of California, Los Angeles, School of Dentistry has identified a protein that plays a key role in the autophagy process that can lead to bone loss.

0

In a development that may have implications for treating periodontal disease, a team from the University of California, Los Angeles, School of Dentistry has identified a protein that plays a key role in the autophagy process that can lead to bone loss.

Published in the Journal of Bone and Mineral Research, the study, “Beclin1 Modulates Bone Homeostasis by Regulating Osteoclast and Chondrocyte Differentiation,” showed that eliminating Beclin1 raises the potential to control the level of bone loss an individual might develop. During the investigation, the team observed several models of Beclin1-enhanced combinations and determined an overexpression of Beclin1 was tied to changes in osteoclast differentiation. In a mouse model in which Beclin1 was eliminated in osteoclasts, the mice experienced thicker cortical bone, researchers report.

Leave A Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy

BLACK FRIDAY / CYBER MONDAY
CE PROMOTION

Coupon has expired

Stay top of your profession with our evidence-based peer-reviewed continuing education courses written by world-class educators and researchers!

Get Black Friday CE Savings!