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A peer-reviewed journal that offers evidence-based clinical information and continuing education for dentists.

The Secret Life of Klebsiella

A new study from the American Dental Association Forsyth Institute reveals that the drug-resistant pathogen Klebsiella thrives in nutrient-deprived conditions common in hospitals. This discovery highlights the importance of understanding the microbial dynamics of oral and nasal cavities, where Klebsiella can reside asymptomatically but can become pathogenic under certain conditions.

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The American Dental Association Forsyth Institute has unveiled groundbreaking research on Klebsiella species, a dangerous multidrug-resistant pathogen responsible for many hospital-acquired infections. The study reveals that Klebsiella, particularly K. pneumoniae, can colonize the oral and nasal cavities of healthy individuals, remaining asymptomatic but capable of turning pathogenic under specific conditions. Notably, the research indicates that these bacteria thrive in nutrient-deprived environments, often found on hospital surfaces, sink drains, and even in the mouths of ventilated patients. These conditions allow Klebsiella to outcompete other microbes, significantly increasing the risk of infection transmission. The study, published in Microbiome, highlights two crucial findings: first, the potential mechanism of Klebsiella transmission via sneezed surfaces, and second, the inherent ability of the healthy oral microbiome to keep these pathogens in check. This study underscores the critical need for further clinical research to confirm these findings and develop more effective infection control strategies in healthcare settings. Click here to read more.

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