A peer-reviewed journal that offers evidence-based clinical information and continuing education for dentists.

Premier Dental and its izzo Named to Fast Company’s Annual List of the World’s Most Innovative Companies for 2023


Premier Dental has been named to Fast Company’s prestigious annual list of the World’s Most Innovative Companies for 2023. This year’s list highlights the businesses at the forefront of their respective industries, paving the way for the innovations of tomorrow. These companies are setting the standard with some of the greatest accomplishments of the modern world. In addition to the World’s 50 Most Innovative Companies, 540 organizations are recognized across 54 sectors and regions.

The first and only of its kind, izzo is more than an ordinary toothbrush. It is a comprehensive system that contains virtually everything patients need to achieve the most optimal oral health in between their dental visits. The system includes:

  • An oscillating electric toothbrush with a timer and three cleaning modes: ultra, daily, and gentle
    • A low abrasive enamel polishing paste and safe “oscillating” polishing cup
    • A high-performance ‘patient-friendly’ scaler with a flexible tip for gentle and safe at-home plaque & soft debris removal
    • A UVC sanitizer that kills 99.9% of germs,*1 including bacteria and viruses

With izzo, professionals and their patients can feel confident in the efficacy of the 4-in-1, as it is based in science and data. The system has been clinically shown to remove stains 73% better than advanced whitening toothpastes,1 with 45% less abrasion.1 Concomitantly, it has 93% better cleaning efficiency than advanced whitening toothpastes.1

Fast Company’s editors and writers sought out the companies making the biggest strides around the globe. They also judged nominations received through their application process.

About izzo

izzo® is the revolutionary 4-in-1 Home Oral Care System that helps patients look and feel their best through healthier, whiter smiles. izzo includes a toothbrush, polishing system (polisher & enamel polishing paste), scaler, and sanitizer. Made by Premier Dental® Products Company, a 4th generation, family-run business established in 1913, izzo reflects the knowledge of over 100 years in developing professional-grade oral care products. This differentiated product introduces innovative at-home dental care directly to patients through an easy-to-use kit and a convenient Subscribe & Save program. For more information, please visit www.izzosmile.com.

*Supported by microbiology testing – Technical Standards for Disinfection, Ministry of Health of PCR, Edition 2002, section 2 ( Guangdong Detection Center of Microbiology

†Based on average stain removal and abrasion of 26 advanced cleaning/whitening toothpastes from leading brands

‡As measured by the Cleaning Efficiency Index (ratio of stain removal to dental abrasion) of 26 advanced cleaning/whitening toothpastes


  1. Data on file
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