
Achieving Predictable Bone Regeneration Without Autogenous Grafts
Combining recombinant human platelet-derived growth factor-BB with composite graft materials offers a promising alternative to traditional autogenous bone harvesting.
AGD Subject Code: 490
EDUCATIONAL OBJECTIVES
After reading this course, the participant should be able to:
- Discuss the principles of guided bone regeneration (GBR) and its role in addressing severe horizontal and vertical ridge defects in implant dentistry.
- Identify the benefits and limitations of autogenous bone grafts compared to composite graft materials such as allografts and xenografts in combination with recombinant human platelet-derived growth factor-BB (rhPDGF-BB).
- Recognize the surgical techniques employed in GBR, including cortical perforations, membrane stabilization, and the application of the PASS principle for optimal outcomes.
- Evaluate the clinical considerations, potential advantages, and limitations of using rhPDGF-BB in challenging bone augmentation procedures, particularly in the esthetic zone.
This course was published in the March/April 2025 issue and expires April 2028. The authors have no commercial conflicts of interest to disclose. This 2 credit hour self-study activity is electronically mediated.
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