Prepare for Medical Emergencies

Medical emergencies may occur during the provision of routine dental procedures. They tend to vary in their cause and nature, which demands that all dental personnel be prepared to respond appropriately. Emergencies may arise due to local anesthesia injections, adverse drug interactions and dental anxiety, as well as other possibilities. In addition, patients with preexisting medical conditions may be prone to acute exacerbations — which could result in life-threatening medical emergencies. Patients with underlying medical conditions, such as angina pectoris, hypertension, bronchospastic disease, seizure disorders and glycemic issues, should be closely watched.

Advances in dentistry and medicine have increased the number of patients with complicated medical histories who present to the dental office for treatment. It is not uncommon to encounter patients who have undergone organ transplants, artificial joint replacements, complex surgical heart valve repairs or coronary artery revascularization. Additionally, the introduction of a wide range of therapeutic options used in dental treatment can increase the likelihood of potential drug interactions. Moreover, comprehensive dental care and advances such as implants and extensive restorative treatment are leading to long-term dental treatment needs that attract a stabilized, yet chronically ill and aging patient population. These factors increase the likelihood of a medical emergency in the dental office.

Older adults and patients with special needs, in particular, are at increased risk for adverse drug reactions and medical emergencies in the dental office. Among seniors, there are many physiologic and pathologic changes that occur over time, and when combined with the deterioration of major organs and systems it makes this population more prone to acute exacerbation of chronic conditions. In addition, aging alters the pharmacokinetics of many drugs, which increases sensitivity, especially in the case of central nervous system depressants.

Another consideration affecting medical emergencies in dental practice is that the increased incidence of obesity and adult-onset diabetes among all age groups may increase risk, as well.¹

Preparing for a medical emergency in the dental office requires organization, preparation, and continual training and review for all office staff. Although keeping the appropriate emergency equipment and drugs on hand is important, the training and expertise of the dental team makes all the difference when responding to a medical emergency. Obtaining an appropriate medical history, with an emphasis on review of systems, medications and allergies is essential.²

A team approach to treating medical emergencies in the office is the foundation of successful care. Early diagnosis and management are the hallmarks for successful outcomes. An organized response with a designated role for each caregiver is mandatory to ensure proper management. Conducting drills and rehearsing emergency situations regularly — in addition to certification in Basic Life Support for Healthcare Providers (BLS-HCP) — will hone the team’s skills. Creating a written protocol of whom to call for help and what information to convey is imperative to ensure these important components of any emergency plan are in place.³

PREPARING FOR EMERGENCIES

Every dental office should have a basic emergency kit with drugs and equipment appropriate to its training level, state regulations, types of patients treated, location and whether sedation is administered.⁴

Oxygen must be available in an “E” cylinder that holds more than 600 liters yet is easily transportable. Oxygen delivery systems for the spontaneously breathing patient include nasal cannula, face mask, nonrebreathing mask with an oxygen reservoir, or the nitrous oxide-oxygen nasal hood. Every office must be able to deliver oxygen under positive pressure for the unconscious, apneic patient. The most effective method is a bag-valve-mask device connected to an oxygen source.

Magill forceps are useful in retrieving foreign objects from the hypopharynx. An automated external defibrillator (AED) is key to providing early defibrillation for patients experiencing ventricular tachycardia. An AED that is easy to use and helps convert arrhythmias to normal sinus rhythm will ensure proper perfusion of vital organs.

A manual aneroid sphygmomanometer with a variety of cuff sizes should be available. Many offices have an automated vital sign monitor that can easily obtain systolic/diastolic blood pressure, mean arterial pressure, heart rate and oxygen saturation. A clock with a second hand is invaluable in determining heart rate and documenting the sequence of events.

Emergency drug kits can either be organized by the dental team or purchased commercially. The composition of these kits will vary according to the needs of the practice. There are critical drugs, however, that should be in every dental office, such as oxygen and epinephrine. Oxygen is the primary drug used during any medical emergency. Increasing arterial oxygen tension improves the perfusion of the peripheral tissues and ensures adequate oxygen to the brain.

Epinephrine is the most important injectable drug in the emergency kit, and is the drug of choice in managing cardiovascular and respiratory manifestations of acute anaphylaxis and treating acute asthma attacks that are nonresponsive to inhalers. Epinephrine is a potent bronchodilator that also increases systemic vascular resistance, arterial blood pressure, heart rate, heart contractility, and coronary and cerebral blood flow.

For the emergency treatment of severe allergic reactions or refractory bronchospasm, epinephrine can be injected intramuscularly as 0.3 ml to 0.5 ml of 1:1000 solution. For offices trained in advanced cardiac life support, an epinephrine 1 mg of 10:000 solution given intravenously is part of the cardiac arrest algorithm.

Diphenhydramine HCl is an antihistamine and is used to treat mild to moderate or delayed onset allergic reactions. It can be administered intravenously (25 mg to 50 mg) to treat a moderate skin reaction, or orally (25 mg to 50 mg) for mild, less severe reactions.

Nitroglycerin is indicated in cases of the acute onset of chest pain caused by angina pectoris or myocardial infarction (MI). It acts by relaxing vascular smooth muscle walls, and causes dilation of veins and arteries. For emergency use, nitroglycerin comes in sublingual tablets and as an aerosol in a liquid pump spray. Pain relief usually occurs within 1 to 2 minutes. If symptoms persist, a diagnosis of MI should be suspected. Systolic blood pressure below 90 mmHg is a contraindication to the administration of nitroglycerin. For patients taking erectile dysfunction medications, nitroglycerin should be administered cautiously due to the possibility of hypotension.

Bronchodilators are used in the treatment of acute bronchospasms caused by asthma attacks. They relax the bronchial smooth muscle walls and inhibit the chemical mediators that are usually released during hypersensitivity reactions. Albuterol is the preferred choice, as it has fewer cardiovascular side effects. Patients with asthmatic histories usually present with their own inhalers, which should be used first.

Aspirin is of paramount importance if an acute MI is suspected. It helps prevent the enlargement of clots in the coronary arteries and thus helps decrease mortality due to its immediate antiplatelet actions. Nonenteric coated aspirin, either a 325 mg dose or four 81 mg tablets, should be chewed and swallowed when MI is suspected.

Hypoglycemia can result from fasting or an insulin/carbohydrate imbalance in patients with diabetes. Glucose in an oral carbohydrate form (e.g., orange juice, chocolate or a nondiet soft drink) can be administered only if the patient is conscious. Oral preparations should not be administered to unconscious patients, as they could lead to airway obstruction and aspiration. There is no place for insulin as an emergency drug in the dental office.

Aromatic ammonia is an irritating respiratory stimulant used to arouse an unconscious syncopal patient. It is available as a vaporole. Additional drugs may be added to emergency kits, but their use should be dictated by the training and educational qualifications of the dental team. These parenteral administered drugs may include:
Glucagon: a drug that addresses hypoglycemia in the unconscious patient
Ephedrine: a vasopressor that treats hypotension
Atropine: an antimuscarinic and anticholinergic drug that elevates heart rate and raises blood pressure
Corticosteroid: used as a secondary drug in the treatment of anaphylaxis
Opioids/Opiates: are used for the treatment of pain associated with MI; examples include morphine or fentanyl
Reversal drugs for sedation/anesthesia: for example, clinicians might use naloxone to reverse the respiratory depressant effects of opioids, and flumazenil to reverse the effects of benzodiazepines
Injectable benzodiazepine: indicated for managing intractable or prolonged seizures

Crisis management education may include assisting with bag-valve-mask ventilation, anticipating drug and equipment needs, monitoring vital signs, and being prepared to take over chest compressions. Creating planned protocols and reviewing medical emergency scenarios as an office are the key for preparedness.^5–7 Table 1 provides drug suggestions for the most common medical emergencies experienced in the dental office.

EMERGENCY MANAGEMENT

Asthma is a common disorder characterized by a hyperreactive airway. The result is a narrowing of the bronchial smooth muscle walls and an increase in airflow resistance. Hence, the acute asthmatic reaction results in bronchospasm that can be fatal if not properly managed. Taking a thorough medical history that specifies whether the asthma is allergic is helpful in predicting its occurrence. If nonallergic, anxiety and fear may be predisposing factors. Knowledge of any allergies and the patient’s medication usage, in addition to history of hospitalization, is essential to the successful management of an asthmatic episode.^8–10

Management starts by evaluating the severity and urgency of the situation. In cases of mild asthma, beta 2 aerosol agonists, such as albuterol, can be administered in addition to supplemental oxygen. Dosage is usually two puffs of either the patient’s own inhaler or an albuterol inhaler from the emergency kit. Symptoms usually subside in 15 to 30 seconds. In severe asthmatic reactions not alleviated by inhalers, emergency medical services should be immediately contacted. If the patient continues to deteriorate, intramuscular epinephrine should be injected.^8–10

Angina pectoris is usually described as a heaviness in the chest and may present with pain radiation to the left shoulder/arm, jaw or back. Pain usually occurs due to atherosclerosis or narrowing of major heart vessels. Stress, anxiety or pain can lead to an event, even in patients with a history of stable angina. Episodes usually last between 5 and 15 minutes. Symptoms can usually be relieved with nitroglycerin in the form of sublingual fast-absorbing tablets or sublingual spray. Drug expiration dates should be checked periodically, as nitrites have a short shelf life. Patients sometimes present with their own nitroglycerin, which should be used first. The usual dose is one to two tablets or two sprays every 5 minutes, not exceeding three doses. Oxygen can also be given during the attack.^8–10

Acute coronary syndrome or MI usually is the result of atherosclerosis in coronary arteries and ischemia in the heart muscle. It can lead to irregular heartbeat or cardiac arrest. Patients present with similar symptoms to angina, but typically symptoms persist for longer than 20 minutes, or the pain is unresponsive to nitroglycerin. If pain is unrelieved by nitroglycerin or if the onset of symptoms is new, the dental team should call 911 immediately. Managing the patient with MI until emergency services arrive consists of administering oxygen and nitroglycerin, and having the patient chew, then swallow one 325 mg tablet of nonenteric-coated aspirin.^8–10

If the patient loses consciousness due to an evolving MI and experiences cardiac arrest, BLS-HCP protocol should immediately begin and continue until help arrives. Chest compressions at a rate of 100 per minute at a ratio of 30 compressions to two ventilations with the use of a bag-valve-mask system connected to a 100% oxygen source should commence. After five cycles of chest compressions, a new rescuer should take over. The presence of an AED for defibrillation can significantly improve survival rates.¹¹

Vasovagal syncope is common in the dental setting among healthy individuals. It usually is precipitated by stressful or anxiety-provoking situations. It may be associated with prodromal symptoms, such as nausea, lightheadedness, increased heart rate, blurred vision, confusion or abdominal pain. Often, repositioning the patient in a supine position — with the head at the same level as the heart, and the legs slightly elevated — prevents loss of consciousness. If transient loss of consciousness occurs, urgent assessment of the airway to confirm air exchange and patency of the airway is essential. The basic airway maneuvers of head tilt, chin lift are employed if necessary. Aromatic ammonia — a respiratory stimulant — can also be used to arouse patients.

A detailed history of preexisting seizure disorder is important, as it provides information regarding type, severity, duration, and medication effectiveness in controlling seizure disorders. Some patients experience a prodromal event, such as an aura that can be visual or olfactory. Some seizures can be initiated with toxic or intravascular doses of local anesthetics. Management is directed at preventing injury and assuring air exchange. If a seizure occurs during treatment, the patient should be repositioned away from sharp objects. Gently holding the patient’s arms and legs can also help prevent injury. Patients may lose consciousness during and after the episode. Seizures related to local anesthetic issues are usually self-limiting. No matter what their etiology, seizures lasting more than 5 minutes are dangerous and require an emergency response. Patients may be disoriented and fatigued, and must be carefully assessed prior to leaving the dental office.

Allergic reactions can vary from mild to severe, and may develop a few seconds or hours after exposure to an allergen. In dentistry, the most common allergens are latex and antibiotics. If the reaction is mild, occurs over time, and only itching and/or rash are seen, an antihistamine may be appropriate. If the reaction is immediate and cascades into respiratory and cardiovascular involvement, then it is life-threatening. Epinephrine is the sole treatment in this situation, and successful outcome is determined by early diagnosis and immediate administration of epinephrine. Epinephrine, via autoinjector, should be administered into the vastus lateralis muscle on the lateral side of the thigh.

During a major allergic reaction, loss of consciousness is common and the airway must be monitored and assisted if necessary. Upon diagnosing an acute and serious allergic response, dental teams should call 911 immediately.¹²

CONCLUSION

Anticipation of medical emergencies is an important aspect of practicing safe dentistry, and clinical dental team members should be trained to immediately diagnose and assist in managing medical emergencies. They should be familiar with basic equipment and critical drugs. Dentists and dental hygienists should always actively monitor their patients for acute changes in their medical conditions, especially patients with complex medical histories. An emergency preparedness plan should be present in each office, where the roles of the dentist, dental hygienists, dental assistants, chairside assistants and front office staff are continually reviewed and updated. Routinely rehearsing medical emergency scenarios and incorporating a team approach to appropriate management will increase the effectiveness of treatment and patient safety.

REFERENCES

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