Platelet-rich Fibrin Studied

Researchers from the University Hospital Frankfurt Goethe University, Nova Southeastern University, University Medical Center, Germany, Universitätsklinikum Düsseldorf, and the Pain Therapy Center in France have released a 15-year retrospective study in the Journal of Oral Implantology evaluating the regenerative properties of platelet-rich fibrin (PRF) therapies.

In their study, “Fifteen Years of Platelet Rich Fibrin in Dentistry and Oromaxillofacial Surgery: How High Is the Level of Scientific Evidence?” researchers examined more than 70 papers that met the study criteria. Overall, 1861 patients were involved in the studies. The team found 38 papers showing PRF as a beneficial tool to enhance bone and soft tissue regeneration, and an additional 17 studies that reported PRF as the sole biomaterial used. In nine studies, PRF therapy showed significant improvement in periodontal probing depths and clinical attachment levels. Seven articles evaluating this approach reported significantly enhanced new bone formation during socket preservation and ridge augmentation.

These findings led the international research team to suggest standardization of PRF protocols in order

From Decisions in Dentistry. February 2019;5(2):8.